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Antibiotic work either to stop or to kill bacteria. They all have been modified to influence the selected bacteria, but not the cells in the body. Considering that bacteria are single-cell organisms, they pass into our immune systems, reproduce inside our bodies and cause disease. If we want to kill the bacteria and eliminate the disease, we have to take antibiotics. But, different types of antibiotics act differently: some inhibit the ability of bacteria to turn glucose into energy and construct the cell wall; others act only on the cell-wall-building mechanism of bacteria... More info
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2) Anti-staphylococcal penicillins They are resistant to staphylococcal beta-lactamase but not to other beta-lactamases produced by gram-negative microbes. The drugs have a very narrow spectrum because the effect against gram-positive bacteria other than staphylococci is weaker comparing to penicillin G. Oxacillin is the only drug registered in the Czech Republic. The daily dosage of oxacillin is 2g - 12g. Remember: Methicillin-resistant strins of Staphylococcus aureus (MRSA) or Staphylococcus epidermidis (MRSE) have changed their PBP receptor and therefore are resistant to all beta-lactam antibiotics. These microbes used to be simultaneously resistant to macrolides and lincosamides. Drug of choice in this situation is vancomycin.. Oxacillin is the only drug registered in the Czech Republic. The daily dosage of oxacillin is 2g - 12g. Remember: Methicillin-resistant strins of Staphylococcus aureus (MRSA) or Staphylococcus epidermidis (MRSE) have changed their PBP receptor and therefore are resistant to all beta-lactam antibiotics. These microbes used to be simultaneously resistant to macrolides and lincosamides. Drug of choice in this situation is vancomycin.
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